The 2022 NFL schedule is out, as the league enters its second year with 17 regular-season games after playing a 16-game schedule since 1978. The regular season kicks off on Thursday, September 8, with the Buffalo Bills visiting the Super Bowl champion Los Angeles Rams. Week 1 also features Russell Wilson's return to Seattle on Monday Night Football, Tom Brady in Dallas, Patrick Mahomes vs. Kyler Murray and six in-division matchups.
Other highlights for the 2022 slate include a Super Bowl LV rematch between the Kansas City Chiefs and Tampa Bay Buccaneers (Oct.